![]() ![]() Treatment on a Stroke Unit or Neuro-ICU is certainly recommended in any of those patients. ![]() Commentsīeyond the identification of acute stroke patients on oral anticoagulation therapy, the type of medication, time since last intake, renal function and laboratory exams as well as the availability of reversal agents have to be considered before rt-PA application and potential endovascular therapy. However, international guidelines can be considered heterogenous or do even lack recommendations on this topic especially in light of available reversal agents. The question how to deal with such patients with regard to intravenous thrombolysis with rt-PA within the 4.5 h time window is of great relevance for daily clinical routine. Despite correct drug intake and good adherence to the respective medication, recurrent ischemic stroke still occurs in ~ 3% of patients. National Library of Medicine.Based on demographical trends and the expected worldwide increase in the number of individuals with atrial fibrillation, the rate of patients who are on oral anticoagulation therapy for secondary prevention of stroke rises continuously. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Idarucizumab Archived at the Wayback Machine, American Medical Association."International nonproprietary names for pharmaceutical substances (INN): recommended INN: list 76". "International nonproprietary names for pharmaceutical substances (INN): recommended INN: list 71". Food and Drug Administration (FDA) (Press release). ^ "FDA approves Praxbind, the first reversal agent for the anticoagulant Pradaxa". ![]()
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